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Citation:

Active mixing during hybridization improves the accuracy and reproducibility of microarray results. BioTechniques Vol. 38, No. 1: pp 117-119 (Jan 2005).

Christopher J. Schaupp, Guojian Jiang, Timothy G. Myers, and Michael A. Wilson

National Institute of Allergy and Infectious Diseases, Bethesda, MD

Click here to download the BioTechniques Article

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Citation:

High-resolution mapping of DNA copy alterations in human chromosome 22 using high-density tiling oligonucleotide arrays. PNAS, Mar 2006; 103: 4534-4539.

Alexander Eckehart Urban, Jan O. Korbel, Rebecca Selzer, Todd Richmond, April Hacker, George V. Popescu, Joseph F. Cubells, Roland Green, Beverly S. Emanuel, Mark B. Gerstein, Sherman M. Weissman, and Michael Snyder

Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT;
Department of Genetics and Molecular Biophysics and Biochemistry Department, Yale University School of Medicine, New Haven, CT;
NimbleGen Systems, Inc., 1 Science Court, Madison, WI 53711;
Departments of Human Genetics, and Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA;
Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA;
The Children’s Hospital of Philadelphia, Philadelphia, PA

Click here to download this PNAS Article

"... ...After denaturation, hybridization was carried out on a MAUI Hybridization System (BioMicro Systems, Salt Lake City) for 18 h at 42°C at the NimbleGen Service Laboratory."

 
     
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Citation:

Microarray-based detection of genetic heterogeneity,antimicrobial resistance, and the viable but nonculturable state in human pathogenic Vibrio spp. PNAS, Dec 2005; 10.1073/pnas.0505033102.

Gary J. Vora, Carolyn E. Meador, Michele M. Bird, Cheryl A. Bopp, Joanne D. Andreadis, and David A. Stenger

Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, Washington, DC
National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA

Click here to download this PNAS article

.".. min at room temperature, and the slides were outfitted with MAUI Mixer DC hybridization chambers (BioMicro Systems, Salt Lake City)...
... microarray, and allowed to incubate for 2 h at 63°C on a MAUI Hybridization System (BioMicro Systems). ..."

 
     
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  Citation:

Disruption of a Plasmodium falciparum gene linked to male sexual development causes early arrest in gametocytogenesis. PNAS, Nov 2005; 102: 16813-16818.

Tetsuya Furuya, Jianbing Mu, Karen Hayton, Anna Liu, Junhui Duan, Louis Nkrumah, Deirdre A. Joy, David A. Fidock, Hisashi Fujioka, Akhil B. Vaidya, Thomas E. Wellems, and Xin-zhuan Su

Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY
Institute of Pathology, Case Western Reserve University, Cleveland, OH
Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA

Click here to download this PNAS article

"... SDS/25% formamide with salmon sperm DNA (180 mg/ml, Invitrogen) by using the MAUI Hybridization System (BioMicro Systems, Salt Lake City)...."

 
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Citation:

Global Expression Profiling Applied to the Analysis of Arabidopsis Stamen Development. Plant Physiology, Sep 2007; 10.1104/pp.107.104422.

Marcio Alves-Ferreira, Frank Wellmer, Aline Banhara, Vijaya Kumar, Jose Luis Riechmann, and Elliot M. Meyerowitz

California Institute of Technology, Division of Biology, Pasadena, CA
Department of Genetics, Federal University of Rio de Janeiro, Av. Prof. Rodolpho Paulo Rocco, Rio de Janeiro, Brazil
.

Click here to download this Plant Physiology article

"... ...was generated from these total RNA preparations and hybridized to mi-croarrays using a MAUI Hybridization System (BioMicro Systems, Salt Lake City, UT) as previously described (Wellmer et al., 2006). The dyes used for labeling RNA from the... ..."

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  Citation:

Lithium Treatment Prevents Neurocognitive Deficit Resulting from Cranial
Irradiation.
Cancer Res., Dec 2006; 66: 11179-11186.

Eugenia M. Yazlovitskaya, Eric Edwards, Dinesh Thotala, Allie Fu, Kate L. Osusky, William O. Whetsell, Jr., Braden Boone, Eric T. Shinohara, and Dennis E. Hallahan

Vanderbilt Microarray Shared Resource, Vanderbilt University School of Medicine, Nashville, TN

Abstract Link to Cancer Research Article:
http://cancerres.aacrjournals.org/cgi/content/abstract/66/23/11179?maxtoshow

"... ...Antibody to...MAUI Hybridization System (four-chamber model;
BioMicro Systems, Inc., Salt Lake City, UT). MEEBO microarrays...antiapoptotic factor in a variety of cell systems (48). NAIP belongs to BIRC proteins... ..."

 
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Citation:

High-Resolution Global Profiling of Genomic Alterations with Long Oligonucleotide Microarray.
Cancer Res. 2004. 64: 4744-4748.

Brennan C, Zhang Y, Leo C, Feng B, Cauwels C, Aguirre AJ, Kim M, Protopopov A, Chin L.

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA

Abstract Link to the Cancer Research Article:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15256441


"Labeled reactions in a volume of 45 ul were pipetted onto Agilent Human 1A oligonucleotide arrays. Hybridization was carried out for 18-20 h at 65oC using the MAUI Hybridization System (BioMicro Systems, Salt Lake City, UT)."

 
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Citation:

Stimulation of baculovirus transcriptome expression in mammalian cells by baculoviral transcriptional activators.
J. Gen.Virol., Aug 2007; 88: 2176 - 2184.

Catherine Y. Y. Liu, Chia Hung Wang, Jui Ching Wang, and Yu Chan Chao

Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan
Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan


Abstract Link to the Journal of General Virology Article:

http://vir.sgmjournals.org/cgi/content/abstract/88/8/2176?maxtoshow=&HITS
=&hits=&RESULTFORMAT=&fulltext=biomicro+systems
&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&fdate=1/1/2003&resourcetype=HWCIT

"... ...with a MAUI Hybridization System BioMicro Systems, and then examined using an Axon...baculovirus gene regulation in mammalian systems difficult, as some transcripts...transient transfection assays in insect systems, it had been shown that gp64 and... ..."

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Citation:

Temporal and differential gene expression of Singapore grouper iridovirus
J. Gen. Virol., Oct 2006; 87: 2907-2915.

Li Ming Chen, Fan Wang, Wenjun Song, and Choy Leong Hew

Department of Biological Sciences, National University of Singapore

Abstract Link to the Journal of General Virology Article:

http://vir.sgmjournals.org/cgi/content/abstract/87/10/2907?maxtoshow

"... ...purification kit Qiagen, the mixtures were hybridized to the SGIV
DNA chip by using the MAUI Hybridization System BioMicro Systems and
incubated overnight at 42C. The hybridizations were repeated on duplicate
arrays with independently prepared... ..."

 
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  Citation:

Competitive Displacement of DNA during Surface Hybridization. Biophys. J., Jan 2007;92: L10-L12.

J. Bishop, C. Wilson, A. M. Chagovetz, and S. Blair

Department of Electrical and Computer Engineering, University of Utah, Salt Lake City, UT

Abstract Link to the Biophysical Journal Article:
http://www.biophysj.org/cgi/content/abstract/92/1/L10?maxtoshow

"
.. ...two-component hybridization for two model systems containing a 20
base wild-type...an SNP sequence. In one of the systems used, the wild-type sequence...into a coverslip provided by BioMicro Systems (Salt Lake City, UT). The temperature... ..."

 
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Citation:

Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor. BMC Dev Biol. 2007; 7: 67. Published online 2007 June 13. doi: 10.1186/1471-213X-7-67.

Saurabh Joshi, Holly Davies, Lauren Porter Sims, Shawn E Levy and Jurrien Dean

Laboratory of Cellular and Developmental Biology, NIDDK, National Institutes of Health, Bethesda, MD, and Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN

Click here to download this BMC Developmental Biology Article

"Utilizing a MAUI Hybridization System (BioMicro Systems, Salt Lake City, UT), the arrays were hybridized (25% formamide, 5 ×SSC, 0.1% SDS, 1 μg poly(A)+ RNA) at 42°C for 16 h and then washed (5 min, 55°C) sequentially with 2 × SSC, 1 ×SSC and 0.1 × SSC, each with 0.1% SDS..."

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Citation:

PfGCN5-Mediated Histone H3 Acetylation Plays a Key Role in Gene Expression in Plasmodium falciparum. Eukaryotic Cell, July 2007; 6: 1219 - 1227.

Long Cui, Jun Miao, Tetsuya Furuya, Xinyi Li, Xin-Zhuan Su, and Liwang Cui

Department of Entomology, The Pennsylvania State University, University Park, PA
Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

Abstract Link to the Eukaryotic Cell Article

http://ec.asm.org/cgi/content/abstract/6/7/1219?maxtoshow=&HITS=&hits=&
RESULTFORMAT=&fulltext=biomicro+systems&andorexactfulltext=and&searchid=
1&FIRSTINDEX=10&fdate=1/1/2003&resourcetype=HWCIT

". ...3). Cy5- and Cy3-labeled probes were mixed and hybridized to DNA microarrays using the MAUI Hybridization System (BioMicro Systems, Salt Lake City, UT)."

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Citation:

"NeuroStem Chip": a novel highly specialized tool to study neural differentiation pathways in human stem cells. BMC Genomics 2007, 8:46 doi:10.1186/1471-2164-8-46.

Sergey V Anisimov*, Nicolaj S Christophersen, Ana S Correia, Jia-Yi Li and Patrik Brundin

Neuronal Survival Unit, Wallenberg Neuroscience Center, Lund University, 221 84 Lund, Sweden

Click here to download this BMC Genomics Article

"...subsequently hybridized with test (Cy3-labeled)/reference (Cy5-labeled) RNA samples (or in reverse dye-labeling order) at 42°C for 17 h using a MAUI Hybridization System (BioMicro Systems Inc., Utah)..."

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Citation:

Adaptive expression responses in the Pol-gamma null strain of S. pombe depleted of mitochondrial genome. BMC Genomics 2007, 8: 323. (15 September 2007)

Chu Z, Li J, Eshaghi M, Karuturi RKMURTHY, Lin K, Liu J

Systems Biology, Genome Institute of Singapore, Singapore
Computational and Mathematical Biology, Genome Institute of Singapore,
College of Life Sciences, Beijing Normal University, China
Department of Biochemistry, Yong Loo Ling School of Medicine, National University of Singapore

Click here to download this BMC Genomics Article

"Equal amounts of Cy3- and Cy5-labeled cDNA was pooled and co-hybridized to a
microarray slide using...a MAUI Mixer (BioMicro Systems, Salt Lake City, UT) at 42°C overnight."

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Citation:

Expression evolution in yeast genes of single-input modules is mainly due to changes in trans-acting factors. Genome Research, Aug 2007; 17: 1161 - 1169.

Daryi Wang, Huang-Mo Sung, Tzi-Yuan Wang, Chih-Jen Huang, Peggy Yang, Tiffany Chang, Yang-Chao Wang, Da-Lun Tseng, Jen-Pey Wu, Tso-Ching Lee, Ming-Che Shih, and Wen-Hsiung Li

Research Center for Biodiversity, Academia Sinica, Taipei, Taiwan;
Genomics Research Center, Academia Sinica, Taipei, Taiwan;
Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan;
Department of Biological Sciences and Roy J. Carver Center for Comparative Genomics, University of Iowa, Iowa City, Iowa
Department of Ecology and Evolution, University of Chicago, Chicago, Illinois

Abstract Link to the Genome Research Article:
http://www.genome.org/cgi/content/abstract/17/8/1161?maxtoshow=&HITS=&hits=&R
ESULTFORMAT=&fulltext=biomicro+systems&andorexactfulltext=and&searchid=1&F
IRSTINDEX=10&fdate=1/1/2003&resourcetype=HWCIT

"... ...to the slide by UV before use. The hybridization of cDNA samples to the probes was done with the MAUI Hybridization System (BioMicro) at 42C for 16 h."

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Citation:

Mapping of transcription factor binding regions in mammalian cells by ChIP: Comparison of array- and sequencing-based technologies. Genome Research, June 2007; 17: 898-909.

Ghia M. Euskirchen, Joel S. Rozowsky, Chia-Lin Wei, Wah Heng Lee, Zhengdong D. Zhang, Stephen Hartman, Olof Emanuelsson, Viktor Stolc, Sherman Weissman, Mark B. Gerstein, Yijun Ruan, and Michael Snyder

Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT;
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT;
Genome Institute of Singapore, Singapore;
Department of Genetics, Yale University School of Medicine, New Haven, CT;
Center for Nanotechnology, NASA Ames Research Center, Moffett Field, CA

Click here to download this Genome Research Article:

"... ...ng/mL human recombinant IFNG (RD Systems #285-IF), or left untreated, for...b every 38-b spacing (NimbleGen Systems of Iceland, LLC), ChIP DNA from...MAUI Hybridization Systems from BioMicro Systems for 1618 h at 42C. PCR product... ..."

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Citation:

Genome-Wide Analysis of KAP1 Binding Suggests Autoregulation of KRAB-ZNFs.
PLoS Genet. 2007 June; 3(6): e89. Prepublished online 2007 April 19. Published online 2007 June 1. doi: 10.1371/journal.pgen.0030089.

Henriette O'Geen, Sharon L Squazzo, Sushma Iyengar, Kim Blahnik, John L Rinn, Howard Y Chang, Roland Green, and Peggy J Farnham

Department of Pharmacology, University of California Davis, Davis, CA;
The Genome Center, University of California Davis, Davis, CA;
Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA;
NimbleGen Systems, Madison, WI

Click here to download the PLoS Genetics Article

"After denaturation, hybridization was carried out in a MAUI Hybridization System (BioMicro Systems, http://www.biomicro.com) for 18 h at 42°C."

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Citation:

Genome-Wide Analysis of Gene Expression During Early Arabidopsis Flower Development. PLoS Genet 2(7): e117. DOI: 10.1371/journal.pgen.0020117.

Frank Wellmer, Marcio Alves-Ferreira, Annick Dubois, Jose Luis Riechmann, Elliot M. Meyerowitz

Division of Biology, California Institute of Technology, Pasadena, CA

Click here to download the PLoS Genetics Article

"...and hybridized for 14 h to microarrays at 48°C using a MAUI Hybridization System (BioMicro Systems, Salt Lake City, Utah) according to the manufacturer’s instructions."

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  Citation:

Virulence Gene and Pandemic Group-Specific Marker Profiling of Clinical Vibrio parahaemolyticus Isolates. J. Clin. Microbio., Feb 2007; 10.1128/JCM.00042-07.

Carolyn E. Meador, Michele M. Bird, Cheryl A. Bopp, Peter Gerner-Smidt, John A. Painter, and Gary J. Vora

Center for Bio/Molecular Science & Engineering Naval Research Laboratory, Washington, DC

Abstract Link to the Journal of Clinical Microbiology Article:
http://jcm.asm.org/cgi/content/abstract/JCM.00042-07v1?maxtoshow=&HIT S=&hits=&RESULTFORMAT=&fulltext=biomicro\+systems&andorexactfulltext= and&searchid=1&FIRSTINDEX=0&fdate=1/1/2002&resourcetype=HWCIT


"... ...outfitted with MAUI Mixer M4 hybridization chambers (BioMicro Systems, Salt Lake City, UT, USA). Hybridization reactions...for 2 h at 63 degrees C on a MAUI Hybridization System (BioMicro Systems)."

 
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  Citation:

Simultaneous Detection of Four Human Pathogenic Microsporidian Species from Clinical Samples by Oligonucleotide Microarray.
J. Clin. Microbio., Aug 2005; 43: 4121-4128.

Zheng Wang, Palmer A. Orlandi, and David A. Stenger

Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, Washington, DC
Center for Food Safety and Applied Nutrition, Food and Drug Administration, Laurel, MD

Abstract Link to the Journal of Clinical Microbiology Article:
http://jcm.asm.org/cgi/content/abstract/43/8/4121?maxtoshow=&HITS=&hi
ts=&RESULTFORMAT=1&andorexacttitle=and&fulltext=biomicro+&andorexactf
ulltext=and&searchid=1135121527511_25133&FIRSTINDEX=0&sortspec=releva
nce&fdate=1/1/2002&resourcetype=1


".. Microarray hybridization was performed in a MAUI Mixer hybridization dual-chamber (BioMicro, Salt Lake City, UT) for 1 h at 58{degrees}C..."

 
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Citation:

Detection and genotyping of Entamoeba histolytica, Entamoeba dispar, Giardia lamblia, and Cryptosporidium parvum by oligonucleotide microarray.
J. Clin. Microbio. 2004; Jul; 42(7):3262-71.

Wang Z, Vora GJ, Stenger DA

Center for Bio/Molecular Science & Engineering, Naval Research Laboratory Washington, DC

Abstract Link to Journal of Clinical Microbiology Article:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15243091


"Microarray hybridization and processing. Oligonucleotide-printed slides were blocked with 3% bovine serum albumin-casein solution (pH 7.4) for 15 min at room temperature, rinsed with distilled water , air dried, and placed in a MAUI Mixer hybridization dual chamber (BioMicroSystems, Salt Lake City, Utah) immediately prior to hybridization." "Hybridization was performed on MAUI Hybridization System (BioMicro) for 1 h at 58 degrees C"

 
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Citation:

Immediate-Early Expression of the Herpes Simplex Virus Type 1 ICP27 Transcript Is Not Critical for Efficient Replication In Vitro or In Vivo.
J Virol. 2004 Oct;78(19):10470-8.

Sun A, Devi-Rao GV, Rice MK, Gary LW, Bloom DC, Sandri-Goldin RM, Ghazal P, Wagner EK

Department of Molecular Biology and Biochemisty and Center for Virus Research, University of California, Irvine

Click here to download this Journal of Virology Article

"In the present series of experiments, we used a two-color nucleic acid microarray resonance light-scattering-based (RLS) method (Genicon Sciences) and a MAUI Hybridization System (BioMicro Systems, Salt lake City, UT)."

"For RLS detection, microarrays were prehybridized and hybridized with cDNA probes for18h and rinsed for scanning with a proprietary HiLight dual-color kit (QIAGEN, Genicon Sciences) at 52°C in a MAUI Mixer hybridization chamber."

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Citation:

Modulation of Cell Cycle-specific Gene Expressions at the Onset of S-Phase Arrest Contributes to the Robust DNA Replication Checkpoint Response in Fission Yeast Mol. Biol. Cell. Mar 2007;10.1091/mbc.E06-10-0928.

Zhaoqing Chu, Juntao Li, Majid Eshaghi, Xu Peng, R. Krishna M. Karuturi, and Jianhua Liu

Genome Institute of Singapore

Click here to download this Molecular Biology of the Cell Article

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A publication describing the MAUI Hybridization System has been published in the peer reviewed scientific journal, Analytical Chemistry:

Gains in sensitivity with a device that mixes microarray hybridization solution in a 25-um-thick chamber. Anal. Chem. 74: 6413-6417.
Adey, N.B., M. Lei, M. T. Howard, J. D. Jensen, D. A. Mayo, D. L. Butel, S. C. Coffin, T. C. Moyer, D. E. Slade, M. K. Spute, A. M. Hancock, G. T. Eisenhoffer, B. K. Dalley, and M. R. McNeely. (2002).

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=
PubMed&list_uids= 12510768&dopt=Abstract


A reprint is available by contacting Katie McDaniel.
 
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"Pharmaceutical Companies' Challenges"

The World Market Research Centre published a report, The Future of Drug Discovery, December 2001, with contributions from BioMicro. An article in this report entitled Pharmaceutical Companies' Challenges discusses the vital role microfluidics play in reducing the time, labor and cost associated with bringing new drugs to market. A copy of this article is available upon request from BioMicro.

World Markets Research Centre (WMRC) is a leading global provider of business-critical information and is relied on by thousands of executives in hundreds of multinational corporations, financial institutions and governments across the world.

Click on the image to the left to view a PDF document of the article.
 
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"Sample Processing with Hydrophobic Microfluidics"
McNeely, M., Spute, M., Tusneem, N., Oliphant, A. J. Assoc. Lab. Auto., 4(4), 30-33, (1999).

Click on the image to the left to view a PDF document of the article.
 
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"Hydrophobic Microfluidics"
McNeely, M., Spute, M., Tusneem, N., Oliphant, A. SPIE Microfluidic Devices & Systems II, Vol. 3877, Sept., 1999.

Click on the image to the left to view a PDF document of the article.

 
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"BioMicro Systems, Inc."
Ellen Seo, Ph.D. Business 2.0 (Korean Edition), September 2000, pp.163-165.

Click on the image to the left to view a PDF document of the article.

 
     
   
   
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"Lab-on-a-Chip: A Revolution in Biological and Medical Science"
Figeys, D., Pinto, D. Analytical Chemistry, 72(9), 330-335, (2000).

 
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"Structurally Programmable Microfluidic Systems"
Ahn, C, Puntambekar, S, Hyoung, J, Hong, C-C., in Micro Total Analysis Systems 2000, 5/14/00, pp. 206-8.

 
     
 
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